Integration of IUR
Open Access

Intelligent knee arthroplasty based on digital twin and mixed reality: system design, collaborative process and prospects

LIN Xuzhi
LIN Xuzhi
School of Public Health, Shanghai Medical College, Fudan University, Shanghai 200032, China
,
WANG Yuan
WANG Yuan
Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
,
YANG Dawei
YANG Dawei
yang.dawei@zs-hospital.sh.cn
Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Shanghai Engineer & Technology Research Center of Internet of Things for Respiratory Medicine, Shanghai Respiratory Research Institution, AI+ Lung Cancer Prevention and Treatment Center, Shanghai 200032, China
Author information
Article notes
Funding

LIN Xuzhi, E-mail: 25301020067@m.fudan.edu.cn

Corresponding author,  YANG Dawei, Tel: 021-64041990, E-mail: yang.dawei@zs-hospital.sh.cn

Received December 19, 2025; Accepted December 29, 2025; Published December 30, 2025
Supported by Noncommunicable Chronic Diseases National Science and Technology Major Project (2024ZD0529300), Science and Technology Commission of Shanghai Municipality Project Fund (20DZ2254400), Municipal Key Courses in Shanghai Universities Project Fund (FDSHZD202409).
Integration of IUR
Open Access
Intelligent knee arthroplasty based on digital twin and mixed reality: system design, collaborative process and prospects
LIN Xuzhi
LIN Xuzhi
School of Public Health, Shanghai Medical College, Fudan University, Shanghai 200032, China
,
WANG Yuan
WANG Yuan
Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
,
YANG Dawei
YANG Dawei
yang.dawei@zs-hospital.sh.cn
Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Shanghai Engineer & Technology Research Center of Internet of Things for Respiratory Medicine, Shanghai Respiratory Research Institution, AI+ Lung Cancer Prevention and Treatment Center, Shanghai 200032, China
Author information

LIN Xuzhi, E-mail: 25301020067@m.fudan.edu.cn

Corresponding author,  YANG Dawei, Tel: 021-64041990, E-mail: yang.dawei@zs-hospital.sh.cn

Article notes
Received December 19, 2025; Accepted December 29, 2025; Published December 30, 2025
Funding
Supported by Noncommunicable Chronic Diseases National Science and Technology Major Project (2024ZD0529300), Science and Technology Commission of Shanghai Municipality Project Fund (20DZ2254400), Municipal Key Courses in Shanghai Universities Project Fund (FDSHZD202409).
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Abstract

The advent of medical robots has transformed the landscape of surgery. Compared to traditional surgical methods, the use of surgical robots provides significant advantages in enhancing precision and reducing the workload for surgeons. However, due to resource constraints, fully automated, end-to-end surgical robots are poised to become a key trend in the development of metaverse medicine. Existing knee surgery robots predominantly operate in a semi-active mode, serving as assistants to surgeons, while a limited number of "fully automated" robots can only achieve full automation during the intraoperative phase. This paper proposes an intelligent knee replacement surgery approach based on digital twin and mixed reality technologies, adopting a model of human pre-operative rehearsal and supervision, machine planning, and robotic execution. This shifts the paradigm from "semi-active" to "semi-automated" (covering the full process), serving as a transitional step toward fully automated end-to-end surgery. By ensuring safety and gaining acceptance from both medical professionals and patients, this approach enables high-quality surgical outcomes. It aligns better with current technological foundations and practical requirements while also offering potential for advancements in quantitative surgical assessment within the realm of metaverse medicine.


Key Words: knee arthroplasty; digital twin; metaverse medicine; surgical robot

Metaverse in Medicine

ISSN: 3006-4236

Volume 2, Issue 4

December 2025

Pages: 1-64

PDF CITE Accesses: 9
Metaverse in Medicine
ISSN: 3006-4236
ZENTIME PUBLISHING CORPORATION LIMITED
On This Page
CITE
On This Page
Abstract