Research Field: Perioperative Brain Protection

Main Academic Achievements:

Dr. XIONG firstly discovers and reports that hyperbaric oxygen, electroacupuncture and inhalation anesthetic pretreatment can induce significant brain protection, explores its mechanism of action and achieves preliminary transformation. He has successively obtained 23 fund projects, including 973, National Key Fund for Nature, and National New Drug Creation. He published 269 SCI treatises in Sci Transl Med, J Am Coll Cardiol, Am J Respir Crit Care Med, J Clin Invest, Anesthesiology, etc. He won the First Prize of National Science and Technology Progress Award.

Also known as

President of Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine

Doctoral Supervisor

Director of Shanghai Key Laboratory of Anesthesia and Brain Function Regulation

Editor-in-Chief of Chinese Journal of Anesthesiology

Associate Editor-in-Chief of J Perioperatvie Medicne

Recipient of National Outstanding Youth Foundation

Distinguished Professor of the Cheung Kong Scholars 

Chief Scientist of Project 973 of the Ministry of Science and Technology

Academic Leader of the Innovation Team of the Ministry of Education and Innovation Team in Key Areas of the Ministry of Science and Technology

Immediate Past President, Chinese Society of Anesthesiology (CSA)

Dr. Lulong Bo primarily focuses on research in sepsis and the regulation of inflammation and immunity during the perioperative period. He has been selected for several prestigious programs, including the Young Talents Program in Science and Technology of the Chinese military, the Shanghai Outstanding Young Medical Talents Program, and the Rising Star Program of the Shanghai Science and Technology Commission. Dr. Bo has published over 60 research articles as the first or corresponding author (including co-authorship) in leading journals such as Critical Care and Chest. He has also contributed three Letters to the Editor published in The New England Journal of Medicine and The Lancet. With an H-index of 27, he serves as the principal investigator for multiple national research projects funded by the National Natural Science Foundation of China, including the Young Scientists Fund and the General Program.

In addition to his research achievements, Dr. Bo has edited or translated 12 academic monographs. He has received the Second Prize of the Shanghai Medical Science and Technology Award and the Second Prize of the National Science and Technology Progress Award.

Dr. Wankun Chen serves as Chief Physician, Professor, and Doctoral Supervisor in the Department of Anesthesiology at Zhongshan Hospital, Fudan University, and as Executive Deputy Director of the Department of Anesthesiology at the Shanghai Geriatrics Center. As principal investigator, he has led three projects funded by the National Natural Science Foundation of China and eight provincial or ministerial-level research projects. He has been recognized as an Outstanding Academic Leader of Shanghai, a Shanghai Medical Rising Star (Distinguished Young Medical Talent), and a recipient of the Shanghai "Pujiang Talent Program."

Dr. Chen’s research focuses on perioperative immune homeostasis and brain protection in critically ill patients, spanning basic, clinical, and translational studies. Over the past five years, he has published 26 SCI-indexed research articles as first or corresponding author (including co-authorship) in high-impact journals such as Proceedings of the National Academy of Sciences, Advanced Science, and British Journal of Anaesthesia, with a cumulative impact factor exceeding 170. He has also served as chief editor or contributing editor for over ten textbooks and academic books. In 2019, he received the First Prize of the Shanghai Science and Technology Progress Award as the second contributor.

Jie Fan, a professor of Surgery and Immunology of University of Pittsburgh, dedicated to the study of the cellular and molecular mechanisms underlying inflammation, trauma, and multiorgan failure, etc. Fan undertakes a number of federally funded research projects in the United States. He is also a member of the editorial board or a contributing reviewer of 48 American and European academic journals, including Nature and Nature Medicine.

Dr. Guo graduated from the Fourth Military Medical University (Xi'an) in 2016 with a bachelor's degree in clinical medicine. In 2019, he graduated from Air Force Medical University (Xi'an) with a master's degree in anesthesiology. He completed his doctorate in anesthesiology at the PLA Medical school (Beijing) in 2024. Currently, he serves as a deputy chief physician in the Department of Anesthesiology at the First Medical Center of the General Hospital of the People's Liberation Army.

His research focus lies in neural circuit research on the mechanism of general anesthesia. He has hosted the Youth Project of the National Natural Science Foundation of China. He has published 13 papers as the first or corresponding author, with 9 of them being SCI papers. Among these SCI papers, 7 have an impact factor of over 5 and 1 has an impact factor of over 10. He has also participated in the second - phase project of the "Exploration Plan" for basic neuroscience research.

Dr. Thomas G. Hedberg is an experienced neuroscientist and neurologist with over 20 years in clinical, clinical pharmacology, and nonclinical regulatory writing/management. He specializes in therapeutic areas such as oncology, cardiovascular diseases, CNS disorders, infectious diseases, dermatology, gastroenterology, and women's health.

Dr. Hedberg has a strong background in administrative organization, project management, and planning within the pharmaceutical industry. He has been a medical writing department head, managing teams during IND submissions and publication planning.

Dr. Hedberg's academic and medical experience includes a visiting professorship at the Albert Einstein College of Medicine, where his research has focused on botulinum neurotoxins for treating intractable epilepsies. He has also published numerous scientific and medical papers across various neurological fields.

Seyed Mehdi Hoseini is a member of the research board at the Biotechnology Research Center at the Yazd Reproductive Sciences Institute and the Blood and Oncology Research Center, both affiliated with Shahid Sadoughi University of Medical Sciences and Health Services in Yazd, Iran. He is also a contributing reviewer for the International Journal of Reproductive BioMedicine (IJRM; Pubmed/ISI indexed) and the Iranian Journal of Pediatric Hematology Oncology (IJPHO; ISI indexed). Dr. Hoseini has published more than 30 SCI papers as the first or corresponding author, focusing on the cellular and molecular mechanisms underlying immune-related reproductive disorders and inflammatory diseases, as well as the immunosuppressive and immunomodulatory properties of Mesenchymal Stem Cells (MSCs), specifically fetal MSCs. His clinical expertise lies in medical genetics, particularly cytogenetic approaches including conventional karyotype and FISH techniques, as well as data analysis of whole-exome and whole-genome sequencing. Since 2014, he has been the director of the Yazd Genome Laboratory at the Khatam Al-Anbia Super Specialty Clinic and the supervisor of the Cytogenetic Laboratory at Shahid Sadoughi Hospital (a referral/public hospital) since 2021.

Mayura Iddagoda is a dual trained Physician (Geriatric and Internal medicine), currently working in Royal Perth Hospital, Western Australia as a Perioperative specialist. His clinical expertise is in the fields of Internal medicine, Geriatrics and Perioperative medicine. He is the author of several international peer reviewed publications and is continuing further research in the filed of perioperative medicine. He completed a master’s degree in perioperative medicine and awarded diploma for perioperative medicine from Australia New Zealand College of Anaesthetics (ANZCA). He is completing his doctoral degree in Perioperative Medicine and Geriatrics at the University of Western Australia.

Si Li, Associate Chief Physician at Nanfang Hospital, Southern Medical University, holds a Ph.D. in Anesthesiology from Sun Yat-sen University and serves as a master's supervisor. She graduated from the seven-year clinical medicine program at Tongji Medical College, Huazhong University of Science and Technology. Her clinical expertise includes ultrasound-guided closure of atrial and ventricular septal defects, anesthesia for cardiac and major vascular surgeries, and anesthesia for pediatric and critically ill patients. From 2014 to 2015, she received clinical research training at Johns Hopkins University.

Dr. Li has led one NSFC project and three provincial-level projects and has published seven SCI-indexed papers as first or corresponding author. She has received multiple awards, including the national championship in the 2011 TCI Competition for Intravenous Anesthesia and top prizes at the National Young Anesthesiologists Academic Forum. She currently serves as Deputy Chair of the 10^th Youth Committee of the Anesthesiology Branch of the Guangdong Medical Association.

Dr. Leng is a Professor of Anesthesiology at The First Hospital of Lanzhou University, China, with a PhD and extensive expertise in perioperative medicine and pharmacological research. She has led three National Natural Science Foundation of China (NSFC) projects and multiple provincial-level grants, publishing nearly 200 papers in SCI/CSCD journals such as Biochemical Pharmacology, Cell Biology and Toxicology, and Chinese Journal of Anesthesiology. An active academic leader, she serves as a Standing Committee Member of the Chinese Medical Doctor Association's Anesthesiology Branch and chairs the Gansu Provincial Anesthesiology and Pain Medicine Committees. Additionally, she holds editorial roles in several key journals, including Chinese Journal of Anesthesiology and Journal of Clinical Anesthesiology. With a strong mentorship record (28 PhD and 94 MSc graduates), she combines clinical, research, and editorial contributions to advance anesthesiology.

Cheng Li, M.D, Ph.D., is a doctoral supervisor, Administrative Director of the National Clinical Key Specialty (Anesthesiology), and a Researcher at the Shanghai Key Laboratory of Anesthesiology and Brain Function Regulation. He has developed ten new technologies focusing on anesthesia, perioperative management, and brain protection for elderly critically ill patients, which have been promoted across multiple hospitals. He pioneered the "Full-Process Management Model for Anesthesia and Perioperative Care of Elderly Patients" in China, which was recognized as an Outstanding Case by the Shanghai Hospital Association in 2023. Dr. Li participated in China's first major National Natural Science Foundation (NSFC) project in the field of anesthesiology and has led his team to receive honors such as the "Shanghai Worker Pioneer Award." He currently holds over 20 academic positions, including Youth Committee Member of the Anesthesiology Branch of the Chinese Medical Association, Executive Committee Member of the Innovation and Promotion Branch of the Chinese Association of Cardiothoracic and Vascular Anesthesiology, Committee Member of the Anesthesiology Branch of the Shanghai Medical Doctor Association, and Academic Editor for Anesthesiology and Perioperative Science.

Dr. Li has achieved a series of significant research accomplishments in the fields of anesthesiology and pain management. Her work focuses on key issues such as perioperative pain management and the mechanisms of chronic pain, with particular emphasis on the prevention and treatment of opioid-induced hyperalgesia (OIH). She has made original breakthroughs in the field of epigenetic regulation, pioneering the application of RNA epigenetics in the study of neuropathic pain. Her research has elucidated the critical roles of various epigenetic modifications, such as m6A methylation, in the regulation of chronic neuropathic pain, with related findings published in high-impact journals including Advanced Science (Impact Factor: 17.521).

Dr. Li has served as principal investigator for nine research projects funded at the national, municipal, and institutional levels. Over the past five years, she has published 37 papers in leading journals such as Advanced Science, Journal of Clinical Investigation, Cell Reports Medicine, Advanced Healthcare Materials, and Redox Biology. She also holds 11 authorized Chinese national invention patents.

Dr. Li serves as principal investigator for three projects funded by the National Natural Science Foundation of China, one project supported by a professional association, three university-level projects, and two hospital-level projects; additionally participates in a major national project funded by the Ministry of Science and Technology.

His research focuses on the regulation of brain function during the perioperative period, mitochondrial dynamics and the mechanisms of general anesthesia, and the relationship between biological rhythms and neurocognitive function.

Dr. Lu has made significant contributions to perioperative organ protection. She has led 15 research projects, including NSFC General Program and Major Program subprojects, key military projects, and provincial-level initiatives.

Her work has been published in leading journals such as JAMA Surgery and has contributed to six major awards, including the First Prize of the Ministry of Education and the First Prize of the Shaanxi Provincial Science and Technology Award.

She has edited or co-edited 16 academic books, holds nine patents, and has received honors such as the Shulan Medical Youth Award, the Shaanxi Youth Science and Technology Award, and the Young Elite Award from the Chinese Association of Integrative Medicine. She has been selected for the "Lijian" Talent Program and recognized as a leading young and middle-aged talent in traditional Chinese medicine science and technology in Shaanxi Province, where she also leads a provincial young innovation team.

Professor Ma has been dedicated to research on perioperative brain protection over the long term. He has published 42 SCI-indexed papers as the first or corresponding author in journals such as PLOS Medicine, Anesthesiology, Journal of Neuroinflammation, and Biomaterials Research, including 10 papers in Chinese Academy of Sciences (CAS) Zone 1 journals, 6 papers in TOP journals, 1 paper with an impact factor (IF) greater than 10, and 13 papers with an IF greater than 5 (total cumulative IF = 204.9), with more than 1,200 citations. He has served as the principal investigator for two General Programs and one Young Scientists Fund project funded by the National Natural Science Foundation of China (NSFC), as well as five provincial and ministerial-level projects. Professor Ma has received several honors, including the Youth Talent Support Project of the Beijing Association for Science and Technology, the "Shuren Anesthesiologist Award" from the Beijing Medical Association, and the Top Talent Award from the Chinese PLA General Hospital. Currently, Professor Ma holds several academic positions, including Member of the Youth Committee of the Anesthesiology Branch of the Chinese Medical Association, Deputy Leader of the Youth Committee of the Anesthesiology Branch of the Beijing Medical Association, and Youth Editorial Board Member of the Journal of Clinical Anesthesiology.

Prof. Min, M.D. is a distinguished anesthesiologist, professor, and doctoral supervisor at Chongqing Medical University. With over 40 years of experience, she specializes in perioperative critical care, pain management, and cardiovascular anesthesia. She has led 4 NSFC projects and published 300+ papers (86 SCI). A pioneer in Chongqing’s anesthesiology field, she holds editorial roles in Chinese Journal of Anesthesiology and other core journals, and serves in key national committees, including the Chinese Society of Cardiothoracic Anesthesiology.

Dr. Miao has served as the principal investigator for three projects funded by the National Natural Science Foundation of China and has published over 30 SCI papers in journals such as British Journal of Anaesthesia, Journal of Neuroinflammation, Journal of Cardiothoracic and Vascular Anesthesia, and Anesthesia & Analgesia. She holds youth leadership roles in the Anesthesiology Branch of the Chinese Medical Association, the Chinese Association of Integrative Medicine, and the Beijing Medical Association. Her research focuses on anesthesia and brain function.

Dr. Zongbin Song has a doctoral degree in Anesthesiology. He has presided over 3 National Natural Science Foundation projects, as well as sub - projects of national major programs and Hunan Provincial Natural Science Foundation projects. He has published papers in journals such as PAIN and ANESTH&ANAL. He is the chief translator of KAPLAN's Essentials of Anesthesia for Non - Cardiac Surgery. He has participated in formulating several expert consensuses and group standards. He has been selected for the Hunan Furong Plan for high - level talents in health (disciplinary leader).

He holds multiple academic positions, including a Youth Committee Member and Secretary of the Anesthesiology Branch of the Chinese Medical Association, a Standing Committee Member of the Ultrasound Branch of the Chinese Society of Cardiovascular Anesthesiology, a Committee Member of the Anesthetic Pharmacology Special Committee of the Chinese Pharmacological Society, a Committee Member and Secretary of the Hunan Anesthesiologists Association, and a Correspondent Editor of Journal of Clinical Anesthesiology.

Dr. Wang is currently a member of the National Committee of the Artificial Intelligence Anesthesiology Branch of the Chinese Society of Cardiothoracic Vascular Anesthesiology, a training object of 333 high-level talents in Jiangsu Province, and a key medical talent in Xuzhou City. He is also a reviewer of European Journal of Clinical and Biomedical Sciences, Chinese Medical Review, and Journal of Medical Equipment.
Also known as
Deputy Chief Physician and Research Secretary, Department of Anesthesiology, Xuzhou Central Hospital
Visiting Scholar, Medical Center of Wake Forest University, Nanjing Medical University
Xuzhou Medical University Master's Tutor
Southeast University Master's Off-campus Tutor

Dr. Xia, a Medical Doctor, Professor, Senior Attending Physician, and PhD supervisor, currently serves as the Director of the Department of Anesthesiology/Pain Management at Renmin Hospital of Wuhan University. Dr. Xia is a leading talent in medicine in Hubei Province and an expert receiving the special government allowances of the State Council. He has chaired seven projects funded by the National Natural Science Foundation of China. Dr. Xia has published or co-authored over 10 academic books and holds dozens of patents. He has published nearly 300 papers as the first author or corresponding author, including almost 100 SCI papers in prestigious international journals such as Advanced Science, Cell Death Dis, Cell Commun Signal, J Am Heart Assoc, EClinicalMedicine, Free Radic Biol Med, Crit Care Med, and more. He was selected as one of the World's Top 2% Scientists 2024. Dr. Xia has significant expertise in the fields of diabetic myocardial ischemia-reperfusion injury and perioperative organ protection.

Dr. Xing has presided over or participated in 3 National Natural Science Foundation projects and multiple provincial - level projects, including key construction projects and scientific research projects in Henan Province. She has won several scientific and technological awards in Henan Province, such as second - class and third - class awards for scientific and technological progress, and first - class awards for medical science and technology.

As a supervisor, she has guided many postgraduate students, and her team won awards in the 2024 China International College Students' Innovation Competition. She has published over 30 papers in SCI, Chinese core, and other key journals as the first or corresponding author, and participated in compiling monographs.

She has been granted multiple invention and utility model patents, with 2 successfully transformed and applied clinically. She has launched several new technical projects, filling provincial gaps and promoting their application. For years, she has hosted national and provincial continuing medical education projects, and participated in domestic and international conferences as a chairperson, speaker, host, or panelist.

Dr. Xu is a Professor of Anesthesiology, Chief Physician, and PhD supervisor. He currently serves as the Director of the Anesthesia Quality Control Center of Jiangxi Province and the Director of the Key Anesthesia Laboratory of Jiangxi Province. With over 40 years of experience in clinical anesthesiology, teaching, and research, Dr. Xu has rich practical experience and excellent medical skills. He specializes in anesthesia for liver transplantation, cardiovascular and elderly critical surgeries, pain management, and ICU monitoring and treatment for critically ill patients. Dr. Xu's main research interests include perioperative anesthesia, cardiac and brain organ protection, blood preservation, and the prevention and treatment of postoperative cognitive dysfunction. In recent years, Dr. Xu has published 33 SCI papers (with the highest Impact Factor of 19.2) and nearly 50 papers in core journals as the corresponding author. He has been granted 10 national patents and co-authored 5 academic books. Dr. Xu has led and participated in more than 20 national and provincial-level research projects, including 5 funded by the National Natural Science Foundation of China.

Dr. Li fang Yang has been highly recognized in the academic and medical fields. She has received awards such as the Outstanding Young Scientist Fund of Shaanxi Provincial Basic Research Plan and the Leading Talent (Innovative Talent) of Xi'an Talent Plan. From 2003 to 2023, she has accumulated rich experience in peri - operative anesthesia for complex and severe infant surgeries, especially in emergency airway management.

Her research focuses on the clinical and basic translational research of pediatric clinical anesthesia and myocardial protection, achieving notable results in improving myocardial ischemia - reperfusion injury with electroacupuncture and in the application of anesthesia and 3D printing technology.

She has published 32 SCI papers, including in prestigious journals like JACC (IF = 15.343) and Eur Heart J (IF = 10.046), as well as 8 Chinese core - journal papers, either as the first or corresponding author. She has presided over 3 National Natural Science Foundation projects and several provincial and municipal scientific research projects. Additionally, she has been involved in translating and compiling many academic works and holds 6 invention patents and 3 utility model patents.

Yuan specializes in mechanisms of chronic pain, sleep-pain comorbidity and precision anesthesia and perioperative management. She has actively participated in international collaboration and exchange (Visiting Scholar at Rutgers University and the University of Florida, USA; Clinical Training at Imperial College London, UK) and was invited to deliver lectures at multiple international academic conferences. Yuan has published over 50 SCI papers in high-impact journals such as Pain and J Clin Anesth, and Awarded multiple honors, including the Science and Technology Progress Award of Henan Province. Currently, she serves as youth member of the Anesthetic Pharmacology Branch, Chinese Pharmacological Society; Youth Editorial Board Member of Journal of International Anesthesiology and Resuscitation; and Journal of Zhengzhou University (Medical Edition).

Dr. Zhang has been engaged in anesthesia for maxillofacial surgeries and the promotion of comfortable dental treatments for a long time and holds a certificate in dental sedation and analgesia from the United States. She introduced the operating room emergency manual, which has become a standard in domestic operating rooms and has transformed emergency protocols in China. Dr. Zhang's research focuses on the basic and clinical studies of the effects of anesthetic drugs on neurodevelopment in children. As the first author or corresponding author, she has published more than 30 SCI papers. She has undertaken 5 general projects funded by the National Natural Science Foundation of China, 1 major national science and technology project on military special medicines. Dr. Zhang currently serves as the Executive Editor of Perioperative Safety and Quality Assuranc and is a standing editorial board member of Chinese Journal of Anesthesiology.

Zhang specializes in metabolic instability in perioperative brain health. He has chaired 4 National Natural Science Foundation projects on perioperative brain health and has been awarded the First-Class Science and Technology Progress Award from Shanghai and the First-Class Teaching Achievement Award from Shanghai Jiao Tong University.

Currently, he serves as Executive Committee Member of the Perioperative Basic and Translational Medicine Branch, Chinese Society of Cardiothoracic and Vascular Anesthesia; Member of the Anesthesia Committee, Chinese Research Hospital Association; Chairperson of the Anesthesia and Brain Function Branch, Shandong Neuroscience Society; Director of the Anesthesia and Brain Function Key Laboratory, Shandong Medical and Health Institute; Academic Editor of Anesthesiology and Perioperative Science, etc. 

Zhao has chaired over 10 National Natural Science Foundation projects and has published more than 50 SCI and core journal articles as the first author or corresponding author. He is the principal writer of the "Top Ten Scientific Issues in Anesthesiology and Perioperative Medicine (2025 edition)" as well as the author of 2 expert consensus documents. He holds 4 invention patents, serves as the chief translator of one book, the deputy chief translator of another, and has contributed to 21 books. He was awarded the "Shuren Anesthesiologist Award" from the Beijing Medical Association and the 2024 Outstanding Contribution in Anesthesiology Youth Award from the Anesthesiology Branch of the Chinese Medical Association.

Currently, he serves as Vice Leader of the Youth Group, Anesthesiology Branch, Chinese Medical Association; Vice Chair and Leader of the Ultrasound Working Group, Anesthesiology Branch, Beijing Medical Association; Review Expert for Capital Health Development Scientific Research Special Project; Expert Editorial Board Member of Clinical Anesthesiology Journal; Expert Editorial Board Member of Journal of International Anesthesiology and Resuscitation; Editorial Board Member of Anesthesiology and Perioperative Science, etc.

Yang Zhang is the Director of Anesthesiology Department of Tianjin Fourth Central Hospital. Zhang has rich experience in anesthesia for the elderly and critically ill patients, who is especially good at managing difficult airway and ultrasound-guided nerve blocks. Zhang graduated from Tianjin Medical University and has studied in Tianjin Medical University General Hospital, Tianjin Chest Hospital, Tianjin Children's Hospital and other hospitals. The research directions of Zhang are as follows: organ protection of sepsis, difficult airway management, the influence of anesthetic drugs on tumor and other related directions, etc.

Seyed Amirhossein Mazhari is a Research Assistant at Azerbaijan Medical University with a focus on diverse medical fields such as Internal Medicine, Cardiovascular Medicine, and Molecular Biology. He is currently pursuing his Doctor of Medicine (MD) and has made significant contributions as a reviewer for multiple scientific journals, reflecting his expertise and active engagement in the research community.

Mazhari's research interests span across a broad spectrum, including Endocrine, Dermatology, Genetics, Immunology, and Cell Signaling, with a particular emphasis on improving patient care and advancing medical treatments. His dedication to medical research is demonstrated through his active involvement in publishing scholarly articles and participating in peer review activities.