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Home Perioperative Precision Medicine Volume 3, 2025 Volume 3, Issue 4
Review Article
Open Access
2025 Dec;3(4):207-215
https://doi.org/10.61189/313450skrqzv

Research progress on pharmacological effects and mechanisms of cycloastragenol

Weiqi Lin
Weiqi Lin
School of Clinical Medicine/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Qin Zhang
Qin Zhang
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Sixu Chen
Sixu Chen
Anesthesia Laboratory and Training Center/School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Xinyi Xie
Xinyi Xie
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Jiayin Wang
Jiayin Wang
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Yutong Sun
Yutong Sun
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Qixiang Xu
Qixiang Xu
xuqixiang@wnmc.edu.cn
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Cuifeng Zhang
Cuifeng Zhang
zhangcuifeng@wnmc.edu.cn
Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui, China.
Address correspondence to
Article notes
Highlights
Qixiang Xu, School of Pharmacology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui Province, China. Tel: +86-18355305112. E-mail: xuqixiang@wnmc.edu.cn. Cuifeng Zhang, School of Anesthesiology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui Province, China. Tel: +86-15551257181. E-mail: zhangcuifeng@wnmc.edu.cn.
Received January 21, 2025; Accepted April 24, 2025; Published December 31, 2025

  • Cycloastragenol exhibits anti-aging, anti-cancer, and anti-fibrosis effects. 

  • Although cycloastragenol shows innovative therapeutic potential, further clinical trials are essential to confirm its clinical applicability.  

  • Cycloastragenol offers innovative therapeutic avenues for enhancing surgical recovery.

Previous Article Next Article
Review Article
Open Access
Research progress on pharmacological effects and mechanisms of cycloastragenol
Weiqi Lin
Weiqi Lin
School of Clinical Medicine/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Qin Zhang
Qin Zhang
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Sixu Chen
Sixu Chen
Anesthesia Laboratory and Training Center/School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Xinyi Xie
Xinyi Xie
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Jiayin Wang
Jiayin Wang
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Yutong Sun
Yutong Sun
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Qixiang Xu
Qixiang Xu
xuqixiang@wnmc.edu.cn
Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
,
Cuifeng Zhang
Cuifeng Zhang
zhangcuifeng@wnmc.edu.cn
Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center/School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui, China.
Address correspondence to
Qixiang Xu, School of Pharmacology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui Province, China. Tel: +86-18355305112. E-mail: xuqixiang@wnmc.edu.cn. Cuifeng Zhang, School of Anesthesiology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui Province, China. Tel: +86-15551257181. E-mail: zhangcuifeng@wnmc.edu.cn.
Article notes
Received January 21, 2025; Accepted April 24, 2025; Published December 31, 2025
Highlights

  • Cycloastragenol exhibits anti-aging, anti-cancer, and anti-fibrosis effects. 

  • Although cycloastragenol shows innovative therapeutic potential, further clinical trials are essential to confirm its clinical applicability.  

  • Cycloastragenol offers innovative therapeutic avenues for enhancing surgical recovery.

2025 Dec;3(4):207-215
doi:https://doi.org/10.61189/313450skrqzv
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Abstract

Cycloastragenol, a key bioactive compound extracted from Astragalus membranaceus, has attracted increasing attention for its therapeutic potential in anti-aging, cancer treatment, and fibrosis prevention. This review summarizes the pharmacological activities of Cycloastragenol at molecular, cellular, and systemic levels, and discusses its efficacy across various disease models and potential perioperative applications. Current evidence demonstrates that Cycloastragenol exerts dose-dependent therapeutic efficacy through specific molecular targets. However, its clinical translation remains limited, particularly in surgical recovery contexts, underscoring the need for further validation through well-designed clinical trials focused on perioperative outcomes.

Keywords: Cycloastragenol, pharmacological effect, mechanisms of action, research progress
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Perioperative Precision Medicine

ISSN: 2957-5443

Volume 3, Issue 4

December 2025

Pages: 116-225

PDF CITE Accesses: 23
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Abstract
The double-edged sword of biomarkers in severe infection: Value and risks of combined detection A case report on ultrasound-guided long-axis out-of-plane approach for difficult neuraxial anesthesia Critical thresholds in perioperative blood pressure management: A precision strategy for preventing postoperative organ complications The dual nature of oxidative stress: DNA damage and immune activation Acupoint selection patterns and clinical evidence for acupuncture in the management of breast cancer-related pain Unveiling the complex network of sepsis and cytokine storms: New perspectives from mechanisms to interventions Combining traditional medicine with modern medicine: The role of acupuncture anesthesia in multidisciplinary pain management From organ preservation to xenotransplantation: Technological pathways toward sustainable organ replacement Dual roles of sphingosine-1-phosphate receptor 3 in inflammation, ischemia-reperfusion injury, and vascular homeostasis Bacterial infection and sepsis-associated inflammation: Mechanistic insights and emerging clinical perspectives
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Perioperative Precision Medicine
ISSN: 2957-5443
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