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Home Perioperative Precision Medicine Volume 3, 2025 Volume 3, Issue 4
Review Article
Open Access
2025 Dec;3(4):122-133
https://doi.org/10.61189/579841iexakc

Research progress on the mechanisms of traditional Chinese medicine extracts in improving acute lung injury in sepsis

Sixu Chen
Sixu Chen
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Jiayin Wang
Jiayin Wang
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Weiqi Lin
Weiqi Lin
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Xinyi Xie
Xinyi Xie
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Yutong Sun
Yutong Sun
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Haiyi Qian
Haiyi Qian
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Yichen He
Yichen He
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Cuifeng Zhang
Cuifeng Zhang
zhangcuifeng@wnmc.edu.cn
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
Address correspondence to
Article notes
Highlights

Cuifeng Zhang, School of Anesthesiology, Wannan Medical College,  Wuhu, Anhui Province, China, No. 22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui  Province, China. Tel: +86-15551257181. E-mail: zhangcuifeng@wnmc.edu.cn.


Received March 5, 2025; Accepted May 12, 2025; Published December 31, 2025

  • The pathogenesis of sepsis-induced acute lung injury is outlined.

  • A comprehensive overview of the role of TCM extracts in sepsis-induced acute lung injury is provided.

  • The clinical application of classical TCM extracts is summarized in detail.

Previous Article Next Article
Review Article
Open Access
Research progress on the mechanisms of traditional Chinese medicine extracts in improving acute lung injury in sepsis
Sixu Chen
Sixu Chen
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Jiayin Wang
Jiayin Wang
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Weiqi Lin
Weiqi Lin
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Xinyi Xie
Xinyi Xie
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Yutong Sun
Yutong Sun
School of Clinical Medicine/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Haiyi Qian
Haiyi Qian
School of Pharmacology/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Yichen He
Yichen He
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
,
Cuifeng Zhang
Cuifeng Zhang
zhangcuifeng@wnmc.edu.cn
School of Anesthesiology/Anesthesia Laboratory and Training Center/Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu, Anhui Province, China.
Address correspondence to

Cuifeng Zhang, School of Anesthesiology, Wannan Medical College,  Wuhu, Anhui Province, China, No. 22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui  Province, China. Tel: +86-15551257181. E-mail: zhangcuifeng@wnmc.edu.cn.


Article notes
Received March 5, 2025; Accepted May 12, 2025; Published December 31, 2025
Highlights

  • The pathogenesis of sepsis-induced acute lung injury is outlined.

  • A comprehensive overview of the role of TCM extracts in sepsis-induced acute lung injury is provided.

  • The clinical application of classical TCM extracts is summarized in detail.

2025 Dec;3(4):122-133
doi:https://doi.org/10.61189/579841iexakc
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Accesses: 44
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Abstract

Acute lung injury (ALI) is a severe and life-threatening condition. Traditional Chinese medicine (TCM) extracts, which are rich in bioactive compounds with demonstrated efficacy against ALI, have exhibited considerable therapeutic potential. This review provides a comprehensive analysis of the therapeutic effects of TCM extracts in mitigating sepsis-induced ALI, synthesizing current evidence on their clinical advantages and the underlying molecular and cellular mechanisms. Furthermore, it outlines the major challenges and unresolved issues in the field, offering insights that may guide future research and enhance the application of TCM in managing sepsis-associated respiratory complications.
Keywords: Traditional Chinese medicine extracts, sepsis, acute lung injury, mechanisms, research progress
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Perioperative Precision Medicine

ISSN: 2957-5443

Volume 3, Issue 4

December 2025

Pages: 116-225

PDF CITE Accesses: 44
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Latest Issue
Abstract
The double-edged sword of biomarkers in severe infection: Value and risks of combined detection A case report on ultrasound-guided long-axis out-of-plane approach for difficult neuraxial anesthesia Critical thresholds in perioperative blood pressure management: A precision strategy for preventing postoperative organ complications The dual nature of oxidative stress: DNA damage and immune activation Acupoint selection patterns and clinical evidence for acupuncture in the management of breast cancer-related pain Unveiling the complex network of sepsis and cytokine storms: New perspectives from mechanisms to interventions Combining traditional medicine with modern medicine: The role of acupuncture anesthesia in multidisciplinary pain management From organ preservation to xenotransplantation: Technological pathways toward sustainable organ replacement Dual roles of sphingosine-1-phosphate receptor 3 in inflammation, ischemia-reperfusion injury, and vascular homeostasis Bacterial infection and sepsis-associated inflammation: Mechanistic insights and emerging clinical perspectives
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Perioperative Precision Medicine
ISSN: 2957-5443
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