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Multi-method fusion for image segmentation in skin disease analysis

Siqi Wang*, Danhong Li*, Yina Zhang*, Yu Wang, Linrong Yuan, Miao Yu, Jianghui Li, Yimeng Wang, Ping  Li

Faculty of Medical Instrumentation, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.

*These authors are co-first authors. 

Address correspondence to: Ping Li, Faculty of Medical Instrumentation, Shanghai University of Medicine and Health Sciences, 279 Zhouzhu Highway, Pudong New Area, Shanghai 201318, China. Tel: +86-13764055848. E-mail: lip@sumhs.edu.cn.

Declaration of ethics: The study was approved by the Ethics Review Committees of the Medical University of Vienna and the University of Queensland. 

Declaration of patient consent: The dataset underwent automated screening using neural networks, followed by multiple manual reviews. All EXIF metadata were removed to eliminate any potentially identifiable information. Therefore, the data are considered anonymized to the best of our knowledge.

DOI: https://doi.org/10.61189/446813bjkhvg

 

Received July 26, 2025; Accepted November 4, 2025; Published December 31, 2025

Highlights

● For the first time, the advantages of two deep learning architectures-SegNet and U-Net-were integrated by averaging their prediction outputs. This ensemble approach overcame the limitations of single models and substantially improved segmentation accuracy. 

● The proposed Ensemble Model outperformed both SegNet and U-Net across all major evaluation metrics, including the Intersection over Union (IoU, 93.73%), Dice coefficient (84.85%), precision (93.93%), and loss (0.63), confirming the effectiveness of multi-method fusion. 

● Considering the complex morphology and indistinct lesion boundaries characteristic of skin diseases, a standardized preprocessing and data augmentation pipeline was developed to enhance the model' s robustness in handling diverse lesion patterns.

Research Article |Published on: 31 December 2025

[Progress in Medical Devices] 2025; 3 (4): 223-233

DOI: https://doi.org/10.61189/446813bjkhvg
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Review of key technologies in ankle rehabilitation robots

Jiajia Zha, Qingyun Meng, Hongtao Shen, Mingxia Wei 

School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.

Address correspondence to: Qingyun Meng, School of Health Science and Engineering, University of Shanghai for Science and Technology, No. 516 Jungong Road, Yangpu District, Shanghai 200093, China. Tel: +86-13761813609. E-mail: mengqy@sumhs.edu.cn.

DOI: https://doi.org/10.61189/730741lcujht

Received May 24, 2025; Accepted July 25, 2025; Published March 24, 2026

Highlights 

● As a primary weight-bearing joint, the ankle is highly susceptible to injury, while neurological disorders such as stroke can further impair its motor function, leading to long-term gait disturbances. 

● Rehabilitation robots can be platform-based or wearable: platforms aid early-stage motion restoration, while wearable designs focus on gait retraining. 

● Control systems must prioritize motion accuracy and safety. Adaptive algorithms boost performance, while bioelectric signal integration enables intention recognition. Coupling with virtual or augmented reality further enhances patient engagement.

Review Article |Published on: 24 March 2026

[Progress in Medical Devices] 2026; 4 (1): 10-21

DOI: https://doi.org/10.61189/730741lcujht
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